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Multivariable analysis to determine if HIV-1 Tat dicysteine motif is associated with neurodevelopmental delay in HIV-infected children in Malawi

BACKGROUND: HIV-1 Tat protein is implicated in HIV-neuropathogenesis. Tat C31S polymorphism (Tat(CS)) has been associated with milder neuropathology in vitro and in animal models but this has not been addressed in a cohort of HIV-infected adults or children. METHODS: HIV viral load (VL) in plasma an...

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Detalles Bibliográficos
Autores principales: Dara, Jasmeen, Dow, Anna, Cromwell, Elizabeth, Sturdevant, Christa Buckheit, Mallewa, Macpherson, Swanstrom, Ronald, Van Rie, Annelies, Prasad, Vinayaka R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683967/
https://www.ncbi.nlm.nih.gov/pubmed/26678821
http://dx.doi.org/10.1186/s12993-015-0083-7