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In silico target fishing and pharmacological profiling for the isoquinoline alkaloids of Macleayacordata (Bo Luo Hui)

BACKGROUND: Some isoquinoline alkaloids from Macleaya cordata (Willd). R. Br. (Bo Luo Hui) exhibited antibacterial, antiparasitic, antitumor, and analgesic effects. The targets of these isoquinoline alkaloids are undefined. This study aims to investigate the compound–target interaction network and p...

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Detalles Bibliográficos
Autores principales: Lei, Qifang, Liu, Haibo, Peng, Yong, Xiao, Peigen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683977/
https://www.ncbi.nlm.nih.gov/pubmed/26691584
http://dx.doi.org/10.1186/s13020-015-0067-4