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Atherosclerosis Susceptibility in Mice Is Independent of the V1 Immunoglobulin Heavy Chain Gene

The V1 (V(H)S107.1.42) immunoglobulin heavy chain gene is thought to be critical in producing IgM natural antibodies of the T15-idiotype that protect against both atherosclerosis and infection from Streptococcus pneumoniae. Our aim was to determine whether genetic loss of the V1 gene increased ather...

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Detalles Bibliográficos
Autores principales: Centa, Monica, Gruber, Sabrina, Nilsson, Daniel, Polyzos, Konstantinos A., Johansson, Daniel K., Hansson, Göran K., Ketelhuth, Daniel F.J., Binder, Christoph J., Malin, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684249/
https://www.ncbi.nlm.nih.gov/pubmed/26564818
http://dx.doi.org/10.1161/ATVBAHA.115.305990