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The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis

During replication, mismatch repair proteins recognize and repair mispaired bases that escape the proofreading activity of DNA polymerase. In this work, we tested the model that the eukaryotic mismatch recognition complex tracks with the advancing replisome. Using yeast, we examined the dynamics dur...

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Detalles Bibliográficos
Autores principales: Haye, Joanna E., Gammie, Alison E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684283/
https://www.ncbi.nlm.nih.gov/pubmed/26684201
http://dx.doi.org/10.1371/journal.pgen.1005719