A Novel Genome-Wide Association Study Approach Using Genotyping by Exome Sequencing Leads to the Identification of a Primary Open Angle Glaucoma Associated Inversion Disrupting ADAMTS17

Closed breeding populations in the dog in conjunction with advances in gene mapping and sequencing techniques facilitate mapping of autosomal recessive diseases and identification of novel disease-causing variants, often using unorthodox experimental designs. In our investigation we demonstrate succ...

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Detalles Bibliográficos
Autores principales: Forman, Oliver P., Pettitt, Louise, Komáromy, András M., Bedford, Peter, Mellersh, Cathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684296/
https://www.ncbi.nlm.nih.gov/pubmed/26683476
http://dx.doi.org/10.1371/journal.pone.0143546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684296/
https://www.ncbi.nlm.nih.gov/pubmed/26683476
http://dx.doi.org/10.1371/journal.pone.0143546

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