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Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection

Staphylococcus aureus is capable of infecting nearly every organ in the human body. In order to infiltrate and thrive in such diverse host tissues, staphylococci must possess remarkable flexibility in both metabolic and virulence programs. To investigate the genetic requirements for bacterial surviv...

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Detalles Bibliográficos
Autores principales: Wilde, Aimee D., Snyder, Daniel J., Putnam, Nicole E., Valentino, Michael D., Hammer, Neal D., Lonergan, Zachery R., Hinger, Scott A., Aysanoa, Esar E., Blanchard, Catlyn, Dunman, Paul M., Wasserman, Gregory A., Chen, John, Shopsin, Bo, Gilmore, Michael S., Skaar, Eric P., Cassat, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684308/
https://www.ncbi.nlm.nih.gov/pubmed/26684646
http://dx.doi.org/10.1371/journal.ppat.1005341