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Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection
Staphylococcus aureus is capable of infecting nearly every organ in the human body. In order to infiltrate and thrive in such diverse host tissues, staphylococci must possess remarkable flexibility in both metabolic and virulence programs. To investigate the genetic requirements for bacterial surviv...
Autores principales: | Wilde, Aimee D., Snyder, Daniel J., Putnam, Nicole E., Valentino, Michael D., Hammer, Neal D., Lonergan, Zachery R., Hinger, Scott A., Aysanoa, Esar E., Blanchard, Catlyn, Dunman, Paul M., Wasserman, Gregory A., Chen, John, Shopsin, Bo, Gilmore, Michael S., Skaar, Eric P., Cassat, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684308/ https://www.ncbi.nlm.nih.gov/pubmed/26684646 http://dx.doi.org/10.1371/journal.ppat.1005341 |
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