Protumoral TSP50 Regulates Macrophage Activities and Polarization via Production of TNF-α and IL-1β, and Activation of the NF-κB Signaling Pathway

Testes-specific protease 50 (TSP50) is abnormally overexpressed in many kinds of cancers and promotes cell proliferation and migration. However, whether TSP50 can influence the tumor microenvironment, especially the function of immune cells in the microenvironment, remains largely unknown. We demons...

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Detalles Bibliográficos
Autores principales: Yang, Cheng, Zhang, Dong-Mei, Song, Zhen-Bo, Hou, Ya-Qin, Bao, Yong-Li, Sun, Lu-Guo, Yu, Chun-Lei, Li, Yu-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684331/
https://www.ncbi.nlm.nih.gov/pubmed/26684869
http://dx.doi.org/10.1371/journal.pone.0145095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684331/
https://www.ncbi.nlm.nih.gov/pubmed/26684869
http://dx.doi.org/10.1371/journal.pone.0145095

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