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Analysis of the Enzymatic Activity of an NS3 Helicase Genotype 3a Variant Sequence Obtained from a Relapse Patient

The hepatitis C virus (HCV) is a species of diverse genotypes that infect over 170 million people worldwide, causing chronic inflammation, cirrhosis and hepatocellular carcinoma. HCV genotype 3a is common in Brazil, and it is associated with a relatively poor response to current direct-acting antivi...

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Detalles Bibliográficos
Autores principales: Provazzi, Paola J. S., Mukherjee, Sourav, Hanson, Alicia M., Nogueira, Mauricio L., Carneiro, Bruno M., Frick, David N., Rahal, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684341/
https://www.ncbi.nlm.nih.gov/pubmed/26658750
http://dx.doi.org/10.1371/journal.pone.0144638