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Analysis of the Enzymatic Activity of an NS3 Helicase Genotype 3a Variant Sequence Obtained from a Relapse Patient
The hepatitis C virus (HCV) is a species of diverse genotypes that infect over 170 million people worldwide, causing chronic inflammation, cirrhosis and hepatocellular carcinoma. HCV genotype 3a is common in Brazil, and it is associated with a relatively poor response to current direct-acting antivi...
Autores principales: | Provazzi, Paola J. S., Mukherjee, Sourav, Hanson, Alicia M., Nogueira, Mauricio L., Carneiro, Bruno M., Frick, David N., Rahal, Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684341/ https://www.ncbi.nlm.nih.gov/pubmed/26658750 http://dx.doi.org/10.1371/journal.pone.0144638 |
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