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Contribution of Peptide Backbone to Anti-Citrullinated Peptide Antibody Reactivity

Rheumatoid arthritis (RA) is one of the most common autoimmune diseases, affecting approximately 1–2% of the world population. One of the characteristic features of RA is the presence of autoantibodies. Especially the highly specific anti-citrullinated peptide antibodies (ACPAs), which have been fou...

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Detalles Bibliográficos
Autores principales: Trier, Nicole Hartwig, Dam, Catharina Essendrup, Olsen, Dorthe Tange, Hansen, Paul Robert, Houen, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684344/
https://www.ncbi.nlm.nih.gov/pubmed/26657009
http://dx.doi.org/10.1371/journal.pone.0144707