Branched-Chain Aminotransferases Control TORC1 Signaling in Saccharomyces cerevisiae

The conserved target of rapamycin complex 1 (TORC1) integrates nutrient signals to orchestrate cell growth and proliferation. Leucine availability is conveyed to control TORC1 activity via the leu-tRNA synthetase/EGOC-GTPase module in yeast and mammals, but the mechanisms sensing leucine remain only...

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Detalles Bibliográficos
Autores principales: Kingsbury, Joanne M., Sen, Neelam D., Cardenas, Maria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684349/
https://www.ncbi.nlm.nih.gov/pubmed/26659116
http://dx.doi.org/10.1371/journal.pgen.1005714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684349/
https://www.ncbi.nlm.nih.gov/pubmed/26659116
http://dx.doi.org/10.1371/journal.pgen.1005714

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