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Branched-Chain Aminotransferases Control TORC1 Signaling in Saccharomyces cerevisiae

The conserved target of rapamycin complex 1 (TORC1) integrates nutrient signals to orchestrate cell growth and proliferation. Leucine availability is conveyed to control TORC1 activity via the leu-tRNA synthetase/EGOC-GTPase module in yeast and mammals, but the mechanisms sensing leucine remain only...

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Detalles Bibliográficos
Autores principales:	Kingsbury, Joanne M., Sen, Neelam D., Cardenas, Maria E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684349/ https://www.ncbi.nlm.nih.gov/pubmed/26659116 http://dx.doi.org/10.1371/journal.pgen.1005714

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