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Understanding Biases in Ribosome Profiling Experiments Reveals Signatures of Translation Dynamics in Yeast

Ribosome profiling produces snapshots of the locations of actively translating ribosomes on messenger RNAs. These snapshots can be used to make inferences about translation dynamics. Recent ribosome profiling studies in yeast, however, have reached contradictory conclusions regarding the average tra...

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Detalles Bibliográficos
Autores principales: Hussmann, Jeffrey A., Patchett, Stephanie, Johnson, Arlen, Sawyer, Sara, Press, William H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684354/
https://www.ncbi.nlm.nih.gov/pubmed/26656907
http://dx.doi.org/10.1371/journal.pgen.1005732