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Melatonin Activates Endoplasmic Reticulum Stress and Apoptosis in Rats with Diethylnitrosamine-Induced Hepatocarcinogenesis

Hepatocellular carcinoma (HCC) is one of the most lethal human cancers worldwide because of its high incidence, its metastatic potential and the low efficacy of conventional treatment. Inactivation of apoptosis is implicated in tumour progression and chemotherapy resistance, and has been linked to t...

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Detalles Bibliográficos
Autores principales: Moreira, Andrea Janz, Ordoñez, Raquel, Cerski, Carlos Thadeu, Picada, Jaqueline Nascimento, García-Palomo, Andrés, Marroni, Norma Possa, Mauriz, Jose L., González-Gallego, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684373/
https://www.ncbi.nlm.nih.gov/pubmed/26656265
http://dx.doi.org/10.1371/journal.pone.0144517