Cargando…
Melatonin Activates Endoplasmic Reticulum Stress and Apoptosis in Rats with Diethylnitrosamine-Induced Hepatocarcinogenesis
Hepatocellular carcinoma (HCC) is one of the most lethal human cancers worldwide because of its high incidence, its metastatic potential and the low efficacy of conventional treatment. Inactivation of apoptosis is implicated in tumour progression and chemotherapy resistance, and has been linked to t...
Autores principales: | Moreira, Andrea Janz, Ordoñez, Raquel, Cerski, Carlos Thadeu, Picada, Jaqueline Nascimento, García-Palomo, Andrés, Marroni, Norma Possa, Mauriz, Jose L., González-Gallego, Javier |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684373/ https://www.ncbi.nlm.nih.gov/pubmed/26656265 http://dx.doi.org/10.1371/journal.pone.0144517 |
Ejemplares similares
-
Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model
por: Rodrigues, Graziella, et al.
Publicado: (2019) -
Oxidative stress and cell damage in a model of precancerous lesions and advanced hepatocellular carcinoma in rats
por: Moreira, Andrea J., et al.
Publicado: (2014) -
Endoplasmic reticulum stress in diethylnitrosamine-induced rat liver cancer
por: XIAO, BIN, et al.
Publicado: (2014) -
Anticancer effect of caudatin in diethylnitrosamine-induced hepatocarcinogenesis in rats
por: Song, Jie, et al.
Publicado: (2020) -
Melatonin restores zinc levels, activates the Keap1/Nrf2 pathway, and modulates endoplasmic reticular stress and HSP in rats with chronic hepatotoxicity
por: Bona, Silvia, et al.
Publicado: (2022)