Rapid Heme Transfer Reactions between NEAr Transporter Domains of Staphylococcus aureus: A Theoretical Study Using QM/MM and MD Simulations

In vertebrates, most iron is present as heme or is chelated by proteins. Thus, Gram-positive pathogens such as Staphylococcus aureus have evolved an iron-regulated surface determinant (Isd) system that transports heme across thick cell walls into the cytoplasm. Recent studies have demonstrated that...

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Detalles Bibliográficos
Autores principales: Moriwaki, Yoshitaka, Terada, Tohru, Tsumoto, Kouhei, Shimizu, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684392/
https://www.ncbi.nlm.nih.gov/pubmed/26658942
http://dx.doi.org/10.1371/journal.pone.0145125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684392/
https://www.ncbi.nlm.nih.gov/pubmed/26658942
http://dx.doi.org/10.1371/journal.pone.0145125

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