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Likelihood Ratio Test for Excess Homozygosity at Marker Loci on X Chromosome
The assumption of Hardy-Weinberg equilibrium (HWE) is generally required for association analysis using case-control design on autosomes; otherwise, the size may be inflated. There has been an increasing interest of exploring the association between diseases and markers on X chromosome and the effec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684405/ https://www.ncbi.nlm.nih.gov/pubmed/26671781 http://dx.doi.org/10.1371/journal.pone.0145032 |