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Likelihood Ratio Test for Excess Homozygosity at Marker Loci on X Chromosome

The assumption of Hardy-Weinberg equilibrium (HWE) is generally required for association analysis using case-control design on autosomes; otherwise, the size may be inflated. There has been an increasing interest of exploring the association between diseases and markers on X chromosome and the effec...

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Detalles Bibliográficos
Autores principales: You, Xiao-Ping, Zou, Qi-Lei, Li, Jian-Long, Zhou, Ji-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684405/
https://www.ncbi.nlm.nih.gov/pubmed/26671781
http://dx.doi.org/10.1371/journal.pone.0145032