An Active 32-kDa Cathepsin L Is Secreted Directly from HT 1080 Fibrosarcoma Cells and Not via Lysosomal Exocytosis

Cathepsin L [EC 3.4.22.15] is secreted via lysosomal exocytosis by several types of cancer cells, including prostate and breast cancer cells. We previously reported that human cultured fibrosarcoma (HT 1080) cells secrete cathepsin L into the medium; this secreted cathepsin is 10-times more active t...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yoko, Kondo, Chihiro, Katunuma, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684495/
https://www.ncbi.nlm.nih.gov/pubmed/26674348
http://dx.doi.org/10.1371/journal.pone.0145067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684495/
https://www.ncbi.nlm.nih.gov/pubmed/26674348
http://dx.doi.org/10.1371/journal.pone.0145067

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