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GTPase Activating Protein (Sh3 Domain) Binding Protein 1 Regulates the Processing of MicroRNA-1 during Cardiac Hypertrophy

BACKGROUND: MicroRNAs (miR) are small, posttranscriptional regulators, expressed as part of a longer primary transcript, following which they undergo nuclear and cytoplasmic processing by Drosha and Dicer, respectively, to form the functional mature ~20mer that gets incorporated into the silencing c...

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Detalles Bibliográficos
Autores principales: He, Minzhen, Yang, Zhi, Abdellatif, Maha, Sayed, Danish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684496/
https://www.ncbi.nlm.nih.gov/pubmed/26675618
http://dx.doi.org/10.1371/journal.pone.0145112