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Integrative genomic analysis reveals functional diversification of APOBEC gene family in breast cancer
BACKGROUND: The human APOBEC protein family plays critical but distinct roles in host defense. Recent studies revealed that APOBECs mediate C-to-T mutagenesis in multiple cancers, including breast cancer. It is still unclear whether APOBEC gene family shows functional diversification involved in can...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684623/ https://www.ncbi.nlm.nih.gov/pubmed/26682542 http://dx.doi.org/10.1186/s40246-015-0056-9 |