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Integrative genomic analysis reveals functional diversification of APOBEC gene family in breast cancer

BACKGROUND: The human APOBEC protein family plays critical but distinct roles in host defense. Recent studies revealed that APOBECs mediate C-to-T mutagenesis in multiple cancers, including breast cancer. It is still unclear whether APOBEC gene family shows functional diversification involved in can...

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Detalles Bibliográficos
Autores principales: Zhang, Yanfeng, Delahanty, Ryan, Guo, Xingyi, Zheng, Wei, Long, Jirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684623/
https://www.ncbi.nlm.nih.gov/pubmed/26682542
http://dx.doi.org/10.1186/s40246-015-0056-9