p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling

Pancreatic cancer (PC) remains a highly lethal malignancy due to its unusual chemoresistance and high aggressiveness. A subpopulation of pancreatic tumor cells, known as cancer stem cells (CSCs), is considered responsible not only for tumor-maintenance, but also for its widespread metastasis and the...

Descripción completa

Detalles Bibliográficos
Autores principales: Tyagi, Nikhil, Marimuthu, Saravanakumar, Bhardwaj, Arun, Deshmukh, Sachin K., Srivastava, Sanjeev K., Singh, Ajay P., McClellan, Steven, Carter, James E., Singh, Seema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684758/
https://www.ncbi.nlm.nih.gov/pubmed/26546043
http://dx.doi.org/10.1016/j.canlet.2015.10.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684758/
https://www.ncbi.nlm.nih.gov/pubmed/26546043
http://dx.doi.org/10.1016/j.canlet.2015.10.028

Ejemplares similares