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Class D β-lactamases do exist in Gram-positive bacteria

Production of β-lactamases of the four molecular classes (A, B, C, and D) is the major mechanism of bacterial resistance to β-lactams, the largest class of antibiotics that have saved countless lives since their inception 70 years ago. Although several hundred efficient class D enzymes have been ide...

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Detalles Bibliográficos
Autores principales: Toth, Marta, Antunes, Nuno Tiago, Stewart, Nichole K., Frase, Hilary, Bhattacharya, Monolekha, Smith, Clyde, Vakulenko, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684797/
https://www.ncbi.nlm.nih.gov/pubmed/26551395
http://dx.doi.org/10.1038/nchembio.1950