Synergistic Stimulation with Different TLR7 Ligands Modulates Gene Expression Patterns in the Human Plasmacytoid Dendritic Cell Line CAL-1

Objective. TLR7 ligation in plasmacytoid dendritic cells is promising for the treatment of cancer, allergy, and infectious diseases; however, high doses of ligands are required. We hypothesized that the combination of structurally different TLR7 ligands exponentiates the resulting immune response. M...

Descripción completa

Detalles Bibliográficos
Autores principales: Hilbert, Tobias, Steinhagen, Folkert, Weisheit, Christina, Baumgarten, Georg, Hoeft, Andreas, Klaschik, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684865/
https://www.ncbi.nlm.nih.gov/pubmed/26770023
http://dx.doi.org/10.1155/2015/948540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684865/
https://www.ncbi.nlm.nih.gov/pubmed/26770023
http://dx.doi.org/10.1155/2015/948540

Ejemplares similares