Cargando…

Activation of the Mammalian Target of Rapamycin in the Rostral Ventromedial Medulla Contributes to the Maintenance of Nerve Injury-Induced Neuropathic Pain in Rat

The mammalian target of rapamycin (mTOR), a serine-threonine protein kinase, integrates extracellular signals, thereby modulating several physiological and pathological processes, including pain. Previous studies have suggested that rapamycin (an mTOR inhibitor) can attenuate nociceptive behaviors i...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jian, Feng, Da-Yun, Li, Zhi-Hua, Feng, Ban, Zhang, Han, Zhang, Ting, Chen, Tao, Li, Yun-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684879/
https://www.ncbi.nlm.nih.gov/pubmed/26770837
http://dx.doi.org/10.1155/2015/394820