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Decreased erythrocyte nucleoside transport and hENT1 transporter expression in glucose 6-phosphate dehydrogenase deficiency

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with erythrocyte sensitivity to oxidative damage and hemolytic crises. In β-thalassemia major, where hemoglobin instability imposes oxidative stress, erythrocytes show reduced hENT1 nucleoside transporter expression and de...

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Detalles Bibliográficos
Autores principales: Al-Ansari, Mohammad, Craik, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684917/
https://www.ncbi.nlm.nih.gov/pubmed/26688730
http://dx.doi.org/10.1186/s12878-015-0038-0