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“Mouse Clone Model” for evaluating the immunogenicity and tumorigenicity of pluripotent stem cells

To investigate the immune-rejection and tumor-formation potentials of induced pluripotent stem cells and other stem cells, we devised a model—designated the “Mouse Clone Model”—which combined the theory of somatic animal cloning, tetraploid complementation, and induced pluripotent stem cells to demo...

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Detalles Bibliográficos
Autores principales: Zhang, Gang, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684929/
https://www.ncbi.nlm.nih.gov/pubmed/26687081
http://dx.doi.org/10.1186/s13287-015-0262-3