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“Mouse Clone Model” for evaluating the immunogenicity and tumorigenicity of pluripotent stem cells
To investigate the immune-rejection and tumor-formation potentials of induced pluripotent stem cells and other stem cells, we devised a model—designated the “Mouse Clone Model”—which combined the theory of somatic animal cloning, tetraploid complementation, and induced pluripotent stem cells to demo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684929/ https://www.ncbi.nlm.nih.gov/pubmed/26687081 http://dx.doi.org/10.1186/s13287-015-0262-3 |