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Methyl-CpG Binding Protein 2 (Mecp2) Regulates Sensory Function Through Sema5b and Robo2

Mutations in the gene encoding the MECP2 underlies Rett syndrome, a neurodevelopmental disorder in young females. Although reduced pain sensitivity in Rett syndrome patients and in partial MeCP2 deficient mice had been reported, these previous studies focused predominantly on motor impairments. Ther...

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Detalles Bibliográficos
Autores principales: Leong, Wan Y., Lim, Zhi H., Korzh, Vladimir, Pietri, Thomas, Goh, Eyleen L. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685056/
https://www.ncbi.nlm.nih.gov/pubmed/26733807
http://dx.doi.org/10.3389/fncel.2015.00481