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Methyl-CpG Binding Protein 2 (Mecp2) Regulates Sensory Function Through Sema5b and Robo2
Mutations in the gene encoding the MECP2 underlies Rett syndrome, a neurodevelopmental disorder in young females. Although reduced pain sensitivity in Rett syndrome patients and in partial MeCP2 deficient mice had been reported, these previous studies focused predominantly on motor impairments. Ther...
Autores principales: | Leong, Wan Y., Lim, Zhi H., Korzh, Vladimir, Pietri, Thomas, Goh, Eyleen L. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685056/ https://www.ncbi.nlm.nih.gov/pubmed/26733807 http://dx.doi.org/10.3389/fncel.2015.00481 |
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