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Haptoglobin gene polymorphisms and interleukin-6 and -8 levels in patients with sickle cell anemia

BACKGROUND: Haptoglobin genotypes, and interleukin-6 and -8 participate in the pathophysiology of sickle cell anemia. The expression of cytokines is regulated by genetic mechanisms however the effect of haptoglobin polymorphisms on these cytokines is not fully understood. This study aimed to compare...

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Detalles Bibliográficos
Autores principales: Pierrot-Gallo, Bruna Spinella, Vicari, Perla, Matsuda, Sandra Satiko, Adegoke, Samuel Ademola, Mecabo, Grazielle, Figueiredo, Maria Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685105/
https://www.ncbi.nlm.nih.gov/pubmed/26408368
http://dx.doi.org/10.1016/j.bjhh.2015.07.006