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B Cells Are Multifunctional Players in Multiple Sclerosis Pathogenesis: Insights from Therapeutic Interventions

Multiple sclerosis (MS) is a severe disease of the central nervous system (CNS) characterized by autoimmune inflammation and neurodegeneration. Historically, damage to the CNS was thought to be mediated predominantly by activated pro-inflammatory T cells. B cell involvement in the pathogenesis of MS...

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Detalles Bibliográficos
Autores principales: Claes, Nele, Fraussen, Judith, Stinissen, Piet, Hupperts, Raymond, Somers, Veerle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685142/
https://www.ncbi.nlm.nih.gov/pubmed/26734009
http://dx.doi.org/10.3389/fimmu.2015.00642