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BMI1, ALDH1A1, and CD133 Transcripts Connect Epithelial-Mesenchymal Transition to Cancer Stem Cells in Lung Carcinoma

Epithelial-mesenchymal transition (EMT) is the underlying mechanism of tumor invasion and metastasis. Evidences from lung cancer cellular models show EMT can trigger conversion to a cancer stem cell (CSC) phenotype. In this study, we assessed mRNA expression levels of EMT-inducing transcription fact...

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Detalles Bibliográficos
Autores principales: Koren, Ana, Rijavec, Matija, Kern, Izidor, Sodja, Eva, Korosec, Peter, Cufer, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685144/
https://www.ncbi.nlm.nih.gov/pubmed/26770215
http://dx.doi.org/10.1155/2016/9714315