A lipasin/Angptl8 monoclonal antibody lowers mouse serum triglycerides involving increased postprandial activity of the cardiac lipoprotein lipase

Lipasin/Angptl8 is a feeding-induced hepatokine that regulates triglyceride (TAG) metabolism; its therapeutical potential, mechanism of action, and relation to the lipoprotein lipase (LPL), however, remain elusive. We generated five monoclonal lipasin antibodies, among which one lowered the serum TA...

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Detalles Bibliográficos
Autores principales: Fu, Zhiyao, Abou-Samra, Abdul B., Zhang, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685196/
https://www.ncbi.nlm.nih.gov/pubmed/26687026
http://dx.doi.org/10.1038/srep18502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685196/
https://www.ncbi.nlm.nih.gov/pubmed/26687026
http://dx.doi.org/10.1038/srep18502

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