Cargando…

Apocynin suppression of NADPH oxidase reverses the aging process in mesenchymal stem cells to promote osteogenesis and increase bone mass

Because of the reduced potential for osteogenesis in aging bone marrow stromal cells, the balance of bone metabolism becomes disrupted, leading to various bone diseases. An increase in reactive oxygen species has been determined to be one of the key factors that accelerates the aging process in BMSC...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jinlong, Ming, Leiguo, Shang, Fengqing, Shen, Lijuan, Chen, Jihua, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685263/
https://www.ncbi.nlm.nih.gov/pubmed/26686764
http://dx.doi.org/10.1038/srep18572