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Apocynin suppression of NADPH oxidase reverses the aging process in mesenchymal stem cells to promote osteogenesis and increase bone mass
Because of the reduced potential for osteogenesis in aging bone marrow stromal cells, the balance of bone metabolism becomes disrupted, leading to various bone diseases. An increase in reactive oxygen species has been determined to be one of the key factors that accelerates the aging process in BMSC...
Autores principales: | Sun, Jinlong, Ming, Leiguo, Shang, Fengqing, Shen, Lijuan, Chen, Jihua, Jin, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685263/ https://www.ncbi.nlm.nih.gov/pubmed/26686764 http://dx.doi.org/10.1038/srep18572 |
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