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The molecular mechanism of photochemical internalization of cell penetrating peptide-cargo-photosensitizer conjugates

In many drug delivery strategies, an inefficient transfer of macromolecules such as proteins and nucleic acids to the cytosol often occurs because of their endosomal entrapment. One of the methods to overcome this problem is photochemical internalization, which is achieved using a photosensitizer an...

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Detalles Bibliográficos
Autores principales: Ohtsuki, Takashi, Miki, Shunya, Kobayashi, Shouhei, Haraguchi, Tokuko, Nakata, Eiji, Hirakawa, Kazutaka, Sumita, Kensuke, Watanabe, Kazunori, Okazaki, Shigetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685267/
https://www.ncbi.nlm.nih.gov/pubmed/26686907
http://dx.doi.org/10.1038/srep18577