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The molecular mechanism of photochemical internalization of cell penetrating peptide-cargo-photosensitizer conjugates
In many drug delivery strategies, an inefficient transfer of macromolecules such as proteins and nucleic acids to the cytosol often occurs because of their endosomal entrapment. One of the methods to overcome this problem is photochemical internalization, which is achieved using a photosensitizer an...
Autores principales: | Ohtsuki, Takashi, Miki, Shunya, Kobayashi, Shouhei, Haraguchi, Tokuko, Nakata, Eiji, Hirakawa, Kazutaka, Sumita, Kensuke, Watanabe, Kazunori, Okazaki, Shigetoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685267/ https://www.ncbi.nlm.nih.gov/pubmed/26686907 http://dx.doi.org/10.1038/srep18577 |
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