Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance

Inflammasomes are multiprotein complexes that include members of the NOD-like receptor family and caspase-1. Caspase-1 is required for the fusion of the Legionella vacuole with lysosomes. Caspase-11, independently of the inflammasome, also promotes phagolysosomal fusion. However, it is unclear how t...

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Detalles Bibliográficos
Autores principales: Caution, Kyle, Gavrilin, Mikhail A., Tazi, Mia, Kanneganti, Apurva, Layman, Daniel, Hoque, Sheshadri, Krause, Kathrin, Amer, Amal O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685268/
https://www.ncbi.nlm.nih.gov/pubmed/26686473
http://dx.doi.org/10.1038/srep18479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685268/
https://www.ncbi.nlm.nih.gov/pubmed/26686473
http://dx.doi.org/10.1038/srep18479

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