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Antibiotic regimen based on population analysis of residing persister cells eradicates Staphylococcus epidermidis biofilms

Biofilm formation is a major pathogenicity strategy of Staphylococcus epidermidis causing various medical-device infections. Persister cells have been implicated in treatment failure of such infections. We sought to profile bacterial subpopulations residing in S. epidermidis biofilms, and to establi...

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Detalles Bibliográficos
Autores principales: Yang, Shoufeng, Hay, Iain D., Cameron, David R., Speir, Mary, Cui, Bintao, Su, Feifei, Peleg, Anton Y., Lithgow, Trevor, Deighton, Margaret A., Qu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685274/
https://www.ncbi.nlm.nih.gov/pubmed/26687035
http://dx.doi.org/10.1038/srep18578