PI3K/Akt signaling pathway triggers P2X7 receptor expression as a pro-survival factor of neuroblastoma cells under limiting growth conditions

The expression of purinergic P2X7 receptor (P2X7R) in neuroblastoma cells is associated to accelerated growth rate, angiogenesis, metastasis and poor prognosis. Noticeably, P2X7R allows the survival of neuroblastoma cells under restrictive conditions, including serum and glucose deprivation. Previou...

Descripción completa

Detalles Bibliográficos
Autores principales: Gómez-Villafuertes, Rosa, García-Huerta, Paula, Díaz-Hernández, Juan Ignacio, Miras-Portugal, Mª Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685307/
https://www.ncbi.nlm.nih.gov/pubmed/26687764
http://dx.doi.org/10.1038/srep18417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685307/
https://www.ncbi.nlm.nih.gov/pubmed/26687764
http://dx.doi.org/10.1038/srep18417

Ejemplares similares