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α-Melanocyte-stimulating hormone ameliorates ocular surface dysfunctions and lesions in a scopolamine-induced dry eye model via PKA-CREB and MEK-Erk pathways

Dry eye is a highly prevalent, chronic, and multifactorial disease that compromises quality of life and generates socioeconomic burdens. The pathogenic factors of dry eye disease (DED) include tear secretion abnormalities, tear film instability, and ocular surface inflammation. An effective interven...

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Detalles Bibliográficos
Autores principales: Ru, Yusha, Huang, Yue, Liu, Huijuan, Du, Juan, Meng, Zhu, Dou, Zexia, Liu, Xun, Wei, Rui Hua, Zhang, Yan, Zhao, Shaozhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685655/
https://www.ncbi.nlm.nih.gov/pubmed/26685899
http://dx.doi.org/10.1038/srep18619