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α-Melanocyte-stimulating hormone ameliorates ocular surface dysfunctions and lesions in a scopolamine-induced dry eye model via PKA-CREB and MEK-Erk pathways
Dry eye is a highly prevalent, chronic, and multifactorial disease that compromises quality of life and generates socioeconomic burdens. The pathogenic factors of dry eye disease (DED) include tear secretion abnormalities, tear film instability, and ocular surface inflammation. An effective interven...
Autores principales: | Ru, Yusha, Huang, Yue, Liu, Huijuan, Du, Juan, Meng, Zhu, Dou, Zexia, Liu, Xun, Wei, Rui Hua, Zhang, Yan, Zhao, Shaozhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685655/ https://www.ncbi.nlm.nih.gov/pubmed/26685899 http://dx.doi.org/10.1038/srep18619 |
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