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Mutant p53: One, No One, and One Hundred Thousand

Encoded by the mutated variants of the TP53 tumor suppressor gene, mutant p53 proteins are getting an increased experimental support as active oncoproteins promoting tumor growth and metastasis. p53 missense mutant proteins are losing their wild-type tumor suppressor activity and acquire oncogenic p...

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Detalles Bibliográficos
Autores principales: Walerych, Dawid, Lisek, Kamil, Del Sal, Giannino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685664/
https://www.ncbi.nlm.nih.gov/pubmed/26734571
http://dx.doi.org/10.3389/fonc.2015.00289