Preclinical rodent toxicity studies for long term use of ceftriaxone

A 6-months rodent toxicology and pharmacokinetic (PK) study was performed to provide supportive safety data for long-term use of intravenous ceftriaxone in a clinical trial in patients with amyotrophic lateral sclerosis (ALS). Ceftriaxone was administered by subcutaneous injection at up to 2 g/kg/da...

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Detalles Bibliográficos
Autores principales: Ratti, Elena, Berry, James D., Greenblatt, David J., Loci, Lorena, Ellrodt, Amy Swartz, Shefner, Jeremy M., Cudkowicz, Merit E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685718/
https://www.ncbi.nlm.nih.gov/pubmed/26705515
http://dx.doi.org/10.1016/j.toxrep.2015.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685718/
https://www.ncbi.nlm.nih.gov/pubmed/26705515
http://dx.doi.org/10.1016/j.toxrep.2015.09.010

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