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Preclinical rodent toxicity studies for long term use of ceftriaxone
A 6-months rodent toxicology and pharmacokinetic (PK) study was performed to provide supportive safety data for long-term use of intravenous ceftriaxone in a clinical trial in patients with amyotrophic lateral sclerosis (ALS). Ceftriaxone was administered by subcutaneous injection at up to 2 g/kg/da...
Autores principales: | Ratti, Elena, Berry, James D., Greenblatt, David J., Loci, Lorena, Ellrodt, Amy Swartz, Shefner, Jeremy M., Cudkowicz, Merit E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685718/ https://www.ncbi.nlm.nih.gov/pubmed/26705515 http://dx.doi.org/10.1016/j.toxrep.2015.09.010 |
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