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Versatile synthesis and biological evaluation of novel 3’-fluorinated purine nucleosides

A unified synthetic strategy accessing novel 3'-fluorinated purine nucleoside derivatives and their biological evaluation were achieved. Novel 3’-fluorinated analogues were constructed from a common 3’-deoxy-3’-fluororibofuranose intermediate. Employing Suzuki and Stille cross-coupling reaction...

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Detalles Bibliográficos
Autores principales: Ren, Hang, An, Haoyun, Hatala, Paul J, Stevens, William C, Tao, Jingchao, He, Baicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685831/
https://www.ncbi.nlm.nih.gov/pubmed/26734098
http://dx.doi.org/10.3762/bjoc.11.272