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Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones
New bifunctional chiral ammonium salts were investigated in an asymmetric cascade synthesis of a key building block for a variety of biologically relevant isoindolinones. With this chiral compound in hand, the development of further transformations allowed for the synthesis of diverse derivatives of...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685908/ https://www.ncbi.nlm.nih.gov/pubmed/26734105 http://dx.doi.org/10.3762/bjoc.11.279 |