Cargando…

Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones

New bifunctional chiral ammonium salts were investigated in an asymmetric cascade synthesis of a key building block for a variety of biologically relevant isoindolinones. With this chiral compound in hand, the development of further transformations allowed for the synthesis of diverse derivatives of...

Descripción completa

Detalles Bibliográficos
Autores principales: Di Mola, Antonia, Tiffner, Maximilian, Scorzelli, Francesco, Palombi, Laura, Filosa, Rosanna, De Caprariis, Paolo, Waser, Mario, Massa, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685908/
https://www.ncbi.nlm.nih.gov/pubmed/26734105
http://dx.doi.org/10.3762/bjoc.11.279