Quetiapine Inhibits Microglial Activation by Neutralizing Abnormal STIM1-Mediated Intercellular Calcium Homeostasis and Promotes Myelin Repair in a Cuprizone-Induced Mouse Model of Demyelination

Microglial activation has been considered as a crucial process in the pathogenesis of neuroinflammation and psychiatric disorders. Several antipsychotic drugs (APDs) have been shown to display inhibitory effects on microglial activation in vitro, possibly through the suppression of elevated intracel...

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Detalles Bibliográficos
Autores principales: Wang, Hanzhi, Liu, Shubao, Tian, Yanping, Wu, Xiyan, He, Yangtao, Li, Chengren, Namaka, Michael, Kong, Jiming, Li, Hongli, Xiao, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685920/
https://www.ncbi.nlm.nih.gov/pubmed/26732345
http://dx.doi.org/10.3389/fncel.2015.00492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685920/
https://www.ncbi.nlm.nih.gov/pubmed/26732345
http://dx.doi.org/10.3389/fncel.2015.00492

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