Cargando…

Quetiapine Inhibits Microglial Activation by Neutralizing Abnormal STIM1-Mediated Intercellular Calcium Homeostasis and Promotes Myelin Repair in a Cuprizone-Induced Mouse Model of Demyelination

Microglial activation has been considered as a crucial process in the pathogenesis of neuroinflammation and psychiatric disorders. Several antipsychotic drugs (APDs) have been shown to display inhibitory effects on microglial activation in vitro, possibly through the suppression of elevated intracel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Hanzhi, Liu, Shubao, Tian, Yanping, Wu, Xiyan, He, Yangtao, Li, Chengren, Namaka, Michael, Kong, Jiming, Li, Hongli, Xiao, Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685920/ https://www.ncbi.nlm.nih.gov/pubmed/26732345 http://dx.doi.org/10.3389/fncel.2015.00492

Ejemplares similares

Citrullinated myelin induces microglial TNFα and inhibits endogenous repair in the cuprizone model of demyelination
por: Standiford, Miranda M., et al.
Publicado: (2021)

Dock3 protects myelin in the cuprizone model for demyelination
por: Namekata, K, et al.
Publicado: (2014)

Myelin Protection by Ursolic Acid in Cuprizone-Induced Demyelination in Mice
por: Honarvar, Fatemeh, et al.
Publicado: (2019)

Age Influences Microglial Activation After Cuprizone-Induced Demyelination
por: Klein, Barbara, et al.
Publicado: (2018)

Oligodendrocyte death and myelin loss in the cuprizone model: an updated overview of the intrinsic and extrinsic causes of cuprizone demyelination
por: Zirngibl, Martin, et al.
Publicado: (2022)

Quetiapine, an Atypical Antipsychotic, Is Protective against Autoimmune-Mediated Demyelination by Inhibiting Effector T Cell Proliferation
por: Mei, Feng, et al.
Publicado: (2012)

Quetiapine Ameliorates Schizophrenia-Like Behaviors and Protects Myelin Integrity in Cuprizone Intoxicated Mice: The Involvement of Notch Signaling Pathway
por: Wang, Hua-ning, et al.
Publicado: (2015)

Strain differences in cuprizone induced demyelination
por: Yu, Qili, et al.
Publicado: (2017)

Catalpol Inhibits Ischemia-Induced Premyelinating Oligodendrocyte Damage through Regulation of Intercellular Calcium Homeostasis via Na(+)/Ca(2+) Exchanger 3
por: Cai, Qiyan, et al.
Publicado: (2018)

Gas6 Increases Myelination by Oligodendrocytes and Its Deficiency Delays Recovery following Cuprizone-Induced Demyelination
por: Binder, Michele D., et al.
Publicado: (2011)

Promoting oligodendroglial-oriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant glioma
por: Wang, Yun, et al.
Publicado: (2017)

Cuprizone Intoxication Results in Myelin Vacuole Formation
por: Joost, Sarah, et al.
Publicado: (2022)

TRPV4 Inhibition Improved Myelination and Reduced Glia Reactivity and Inflammation in a Cuprizone-Induced Mouse Model of Demyelination
por: Liu, Meiying, et al.
Publicado: (2018)

Histological validation of fast macromolecular proton fraction mapping as a quantitative myelin imaging method in the cuprizone demyelination model
por: Khodanovich, Marina Yu, et al.
Publicado: (2017)

The Effect of Aerobic Training With the Consumption of Probiotics on the Myelination of Nerve Fibers in Cuprizone-induced Demyelination Mouse Model of Multiple Sclerosis
por: Sajedi, Donya, et al.
Publicado: (2023)

Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination
por: Wang, Yumeng, et al.
Publicado: (2023)

A New Model of Cuprizone-Mediated Demyelination/Remyelination
por: Sachs, Hilary H., et al.
Publicado: (2014)

Cuprizone does not induce CNS demyelination in nonhuman primates
por: Chen, Zhihong, et al.
Publicado: (2015)

An Alternative Cuprizone-Induced Demyelination and Remyelination Mouse Model
por: Zhen, Wei, et al.
Publicado: (2017)

Effect of Fasudil on remyelination following cuprizone‐induced demyelination
por: Wang, Jing, et al.
Publicado: (2019)

Ferroptosis: copper-iron connection in cuprizone-induced demyelination
por: Jhelum, Priya, et al.
Publicado: (2021)

GAS6 Enhances Repair Following Cuprizone-Induced Demyelination
por: Tsiperson, Vladislav, et al.
Publicado: (2010)

Effects of intraventricular methotrexate administration on Cuprizone-induced demyelination in mice
por: Mueller, Andre M., et al.
Publicado: (2013)

Astrogliosis during acute and chronic cuprizone demyelination and implications for remyelination
por: Hibbits, Norah, et al.
Publicado: (2012)

Spatio-Temporal Patterns of Demyelination and Remyelination in the Cuprizone Mouse Model
por: Tagge, Ian, et al.
Publicado: (2016)

Thalamocortical-auditory network alterations following cuprizone‐induced demyelination
por: Ghaffarian, Nikoo, et al.
Publicado: (2016)

Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model
por: Berghoff, Stefan A., et al.
Publicado: (2017)

Five Decades of Cuprizone, an Updated Model to Replicate Demyelinating Diseases
por: Vega-Riquer, Jose M., et al.
Publicado: (2019)

Clozapine administration enhanced functional recovery after cuprizone demyelination
por: Templeton, Nikki, et al.
Publicado: (2019)

Retraction: Effect of Fasudil on remyelination following cuprizone‐induced demyelination.
por: Wang, Jing, et al.
Publicado: (2020)

Delayed Demyelination and Impaired Remyelination in Aged Mice in the Cuprizone Model
por: Gingele, Stefan, et al.
Publicado: (2020)

Cuprizone feed formulation influences the extent of demyelinating disease pathology
por: Toomey, Lillian M., et al.
Publicado: (2021)

Cuprizone-induced Demyelination in Mouse Brain is not due to Depletion of Copper
por: Morgan, Megan L., et al.
Publicado: (2022)

EGF-Coupled Gold Nanoparticles Increase the Expression of CNPase and the Myelin-Associated Proteins MAG, MOG, and MBP in the Septal Nucleus Demyelinated by Cuprizone
por: Lira-Diaz, Eduardo, et al.
Publicado: (2022)

Galanin Transgenic Mice with Elevated Circulating Galanin Levels Alleviate Demyelination in a Cuprizone-Induced MS Mouse Model
por: Zhang, Lin, et al.
Publicado: (2012)

Dietary Vitamin D3 Supplements Reduce Demyelination in the Cuprizone Model
por: Wergeland, Stig, et al.
Publicado: (2011)

Cuprizone demyelination induces a unique inflammatory response in the subventricular zone
por: Hillis, James M., et al.
Publicado: (2016)

Effect of Sox10 on remyelination of the hippocampus in cuprizone‐induced demyelinated mice
por: Shao, Yu, et al.
Publicado: (2020)

Sex Differences in the Behavioural Aspects of the Cuprizone-Induced Demyelination Model in Mice
por: Paton, Kelly F., et al.
Publicado: (2022)

Immunofluorescence assay for demyelination, remyelination, and proliferation in an acute cuprizone mouse model
por: Clawson, Elizabeth D., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_cqag36upn6ob6gt406i8rqcat1