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Halofuginone Synergistically Enhances Anti-Proliferation of Rapamycin in T Cells and Reduces Cytotoxicity of Cyclosporine in Cultured Renal Tubular Epithelial Cells

Both rapamycin (RAPA) and cyclosporin A (CsA) are commonly used for immunosuppression, however their adverse side effects limit their application. Thus, it is of interest to develop novel means to enhance or preserve the immunosuppressive activity of RAPA or CsA while reducing their toxicity. Halofu...

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Detalles Bibliográficos
Autores principales: Chu, Tony L. H., Guan, Qiunong, Nguan, Christopher Y. C., Du, Caigan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686009/
https://www.ncbi.nlm.nih.gov/pubmed/26671563
http://dx.doi.org/10.1371/journal.pone.0144735